I urge you to read about the glymphatic system!
The glymphatic system is thought to be the sewage plumbing of the brain, this have years described but recently has showed importance , since it explains somehow the beta amyloid protein (Parkinson's) are being discarded, and the lewy bodies (Alzheimer's) as well and some how explains how the dementia is related to the normal tension hidrochepalus, an issue that wasn't clearly explained before.
A new chapter for medicine and neurosurgery and neurology would be written!
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http://link.springer.com/article/10.1007/s11064-015-1581-6